What is Tirzepatide?
Tirzepatide is a cutting-edge medication that allows patients to address weight management in a way that was previously thought to be unattainable. While Tirzepatide initially garnered attention for its effectiveness in managing blood sugar levels, it soon revealed its potential in another crucial aspect of health - weight management.
Tirzepatide is a once-weekly medication primarily approved by the FDA in May 2022 for the treatment of Type 2 diabetes. However, its benefits don't just stop there. When combined with the right diet and lifestyle changes, Tirzepatide has shown promise in aiding patients with chronic weight management. In fact, in November 2023, it was formally approved by the FDA for the treatment of obesity. When comparing Tirzepatide vs. Semaglutide for weight loss, in some patients. Tirzepatide resulted in more significant weight loss results than semaglutide.
Tirzepatide is a dual function GLP1/GIP receptor agonist, that is taken in the form of once-weekly subcutaneous injection. Together, these functions can help reduce hunger, causing you to eat less food and lose more weight.
In clinical trials, Tirzepatide has been shown to produce significant weight loss in individuals with obesity, as well as improvements in other markers of health such as blood sugar control and cardiovascular risk factors.
How Does Tirzepatide Work?
Tirzepatide works by targeting the dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist, making it the first weight loss and diabetes care medication that targets 2 receptor agonists. These processes slow down digestion, improve glycemic control and help people feel more full for longer after eating meals. All of this can lead to body weight reduction and weight control.
GIP is a hormone that stimulates the release of insulin, which not only helps control blood sugar levels, but also promotes muscle growth by encouraging protein build-up and discouraging protein breakdown in muscle tissue.
Tirzepatide works by allowing GIP and GLP-1 to stimulate the pancreas to increase the amount of insulin released in response to meals, encouraging healthy blood glucose regulation.
How Does Semaglutide Work?
Semaglutide mimics a hormone called glucagon-like peptide-1 (or GLP-1) that targets areas in the brain that regulate appetite and food intake. Your digestive tract releases this incretin hormone after you’ve eaten a meal, lowering your blood sugar by triggering insulin release to more efficiently manage blood sugar levels. Doing so helps control appetite, and patients taking Semaglutide for weight loss can lose up to one to two pounds per week. Diet and exercise is key to results, as maintaining healthy eating habits is necessary..
Weight Loss with Tirzepatide
How Does Tirzaptide Aid in Weight Loss?
Tirzepatide has garnered attention for its promising outcomes, especially concerning weight management. This treatment not only focuses on weight loss but extends to an array of health improvements, leading to an enhanced quality of life. It's not just about shedding pounds; it's about paving the way for a more balanced, healthy, and energetic life.
When considering Tirzepatide for weight management, some of the potential benefits include:
Weight Reduction: Patients have reported significant weight loss over time.
Improved Blood Sugar Levels: Even if you're not diabetic, stable blood sugar levels can contribute to better overall health.
Enhanced Energy: With weight loss and better sugar control, many patients report feeling more energized.
Appetite Control: Helps in managing hunger, reducing overeating tendencies.
Apetite Control
Tirzepatide affects the brain's appetite-regulating centers, resulting in less hunger and longer sense of fullness. This can lead to a reduction in food intake.
Increased Energy Expenditure
Tirzepatide has been linked to an increase in physical activity. Weight loss is inevitable if the body burns more calories than the caloric intake.
Lipolysis
Tirzepatide has been proven to increase fat cell breakdown, also known as lipolysis. Releasing stored fat to produce energy is fundamental for weight loss.
Slowed Gastric Emptying
Tirzepatide slows down how fast food travels through your digestive tract. This may help you feel fuller longer and aid in food intake management.
Improved Insulin
Tirzepatide enhances insulin sensitivity, which means that the cells in the body are more sensitive to the actions of insulin. Increased insulin sensitivity can improve glucose absorption by cells while decreasing glucose synthesis by the liver. This kind of healthy blood sugar regulation is important for weight loss.
Key Advantages of Tirzepatide Therapy |
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Significant improvement in cardiovascular risk factors associated with obesity |
Slowed gastric emptying in the intestines to help you feel full for longer |
A promoted sensation of fullness sensed by the brain |
Reduced glucagon levels in fasting and after eating |
Enhanced insulin synthesis and secretion |
Suppressed appetite |
Reduced body weight, lipids, blood pressure, and oxidative stress |
Lower blood sugar without any increase in hypoglycemia |
Reduces Inflammatory Biomarkers |
Benefits of Tirzepatide
Tirzepatide Frequently Asked Questions
Tirzepatide is a medication that contributes to weight loss by mimicking the action of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors, signaling satiety and reducing appetite. It works by decreasing appetite, prolonging feelings of fullness, and modulating fat utilization. Here's how tirzepatide contributes to weight loss:
Mimicking GLP-1 and GIP Receptors: Tirzepatide mimics the action of GLP-1 and GIP receptors, signaling satiety and reducing appetite.
Decreasing Appetite: Tirzepatide promotes weight loss by decreasing appetite, leading to reduced food intake.
Modulating Fat Utilization: Tirzepatide has been shown to modulate fat utilization, contributing to weight loss.
Increased Energy and Physical Activity: Tirzepatide can potentially lead to increased energy, encouraging individuals to move more and burn more calories throughout the day.Tirzepatide typically shows weight loss effects after sustained treatment. Here's a brief timeline:
Initial Effects: Many individuals start noticing weight loss effects with tirzepatide relatively early in their treatment, but the exact timeframe can vary due to factors like dosage and individual response.
Sustained Treatment: Participants in studies achieved a significant weight reduction of 20.9% after 36 weeks of taking Tirzepatide at the maximum tolerated dose.
Intensive Lifestyle Intervention: Another study showed an additional 21.1% weight loss after 12 weeks of intensive lifestyle intervention alongside tirzepatide.
Long-Term Maintenance: Continued treatment for 36 weeks with tirzepatide maintained weight loss, highlighting its efficacy for sustained results.
Tirzepatide demonstrates weight loss effects with noticeable changes during sustained treatment, especially over several weeks.
Take Tirzepatide on the same day every week, at any time, with or without meals.
Common Side effects may include nausea, vomitting, diarrhea, and consipation. Medication to help manage side effects are included with our weight loss programs.
Tirzepatide has shown effectiveness in maintaining body weight reduction over time. Clinical trials with 300 participants revealed that 89.5% of those on Tirzepatide maintained weight loss compared with 9.9% on placebo.
Tirzepatide has shown significant weight loss effects in clinical trials. The amount of weight loss can vary, but here are key findings:
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Those treated with tirzepatide experienced weight loss ranging from 34lbs to 48lbs.
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A phase 3 trial demonstrated a 20% reductio in body weight over 72 weeks with tirzepatide.
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Lilly's tirzepatide achieved up to 15.7% weight loss in adults with obesity.
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After 12 weeks of intensive lifestyle intervention, tizepatide showed an additional 21.1% weight loss, totaling a mean weight loss of 26.6%
There may be differences in individual results.
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The US brand names for tirzepatide are Mounjaro and Zepbound.
Start your journey today
If you want to learn about Tirzepatide and whether or not it is right for you, schedule a free consultation with us today. You can request an appointment online, or you can call our office, and we’ll be glad to help.
When you request an appointment online, please be aware that your selected time and date are pending our approval. Your appointment is not confirmed until you receive a confirmation from us. If you would like to have a confirmed appointment immediately, we recommend calling our office directly to schedule. Your patience and understanding are greatly appreciated as we work to confirm your requested appointment.
New patient weight loss appointments are available Monday, Wednesday, and Thursday - Please select New Patient option when requesting appointment
